Published 2002, (AACC Publication),
James T Wu
This new book introduces new tumour markers, including cytokines, growth factors, oncoproteins and mutated suppressor proteins involved in the signal transduction pathway, the cell cycle, and apoptosis. The book also reviews other new tumour markers - angiogenic factors, adhesion molecules, and molecules that are associated with certain types and properties of tumour cells - and describes ELISAs developed for most of them. These new tumour markers differ from currently used tumour markers in that they have the potential for target identification to facilitate more effective target therapy. They may also be used to detect tumours at early or benign states and to predict prognosis, assisting in the design of therapeutic strategy.