Published 1997, 144pp, 45 figures
Peter Pannall and Dusan Kotasek
Samples from patients with malignancy form a significant part of the work load of most hospital laboratories. Molecular biological techniques have opened up new areas of research and applications are beginning to appear in clinical laboratories. This book goes beyond the laboratory aspects to consider the nature, behaviour and management of malignancy. An outline of the genetic changes that lead to the development of a tumour and influence its behaviour are followed by a review of the non-specific biochemical abnormalities that may occur in patients with cancer and their place in diagnosis and management. There are chapters on tumour markers, paraneoplastic syndromes, and the treatment of cancer which consider the options available and the associated problems.